Sunday, 4 September 2011

How is glucose regulated in the circulation of dogs?

Carbohydrate metabolism. The hormone insulin plays a central role in regulating carbohydrate metabolism. Food is digested and broken down into its basic building blocks, one of which is glucose. Glucose is absorbed into the circulation. Rising blood glucose levels stimulates the pancreas to produce insulin. Insulin is released into circulation where it facilitates glucose uptake by cells for use as fuel. Insulin facilitates the storage of glucose as glycogen in liver and muscle cells. When blood glucose levels fall glycogen is converted back to glucose and released back into the circulation. Glucose is filtered into the nephron but is resorbed back into the circulation at the distal tubule.

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